As cells age, they become larger and less capable of reproduction, undergoing changes that eventually result in the loss of cellular identity.
In 1929, Sir Arthur Harden and Hans von Euler-Chelpin shared Nobel Prize in Chemistry for discovering NAD+. NAD+ (Nicotinamide adenine dinucleotide), is a critical coenzyme found in every cell in your body. It is indispensable for life, and is essential to cellular metabolism, the chemistry that keeps you up and running. NAD+ levels and sirtuins function naturally decline as we age.
NAD+, or nicotinamide adenine dinucleotide, is a critical coenzyme found in every cell in your body, and it's involved in hundreds of metabolic processes. It's a critical coenzyme found in every cell in human body that's involved in hundreds of metabolic processes like cellular energy and mitochondrial health. NAD+ is a substrate for DNA repair proteins such as PARP1, PARP2 and PARP3 as well as enzymes that can influence DNA repair capacity such as SIRT1 and SIRT6. Sirtuins are the longevity proteins. Scientist has discovered that, SIR2, a sirtuin in yeast, extended the life of the yeast only when it was activated by NAD+. Metabolism of fatty acids and glucose requires NAD+ function as a hydrogen/electron transfer molecule. Therefore, NAD+ plays a vital role in energy production. In addition, NAD+ also functions as a cosubstrate for post-translational modifications such as deacetylation and ADP-ribosylation, but the body doesn't have an endless supply of NAD+. In fact, it actually declines with age. Maintaining NAD+ levels and getting more NAD+ from supplements are crucial for human body to perform at optimal level.
Dr. David Sinclair discovered that the mice feeding with NMN have their lifespan extended over 20% comparing to those were not feeding with NMN. Dr. Sinclair takes NMN himself to reverse the biological clock and to restore optimal health.
NMN stands for nicotinamide mononucleotide, a molecule naturally occurring in all life forms. NMN is the direct precursor of the essential molecule nicotinamide adenine dinucleotide (NAD+) and is considered a key component to increase NAD+ levels in cells. Science publication suggests that DNA repair is essential for life, yet its efficiency declines with age. Dr. David Sinclair, the lead author of the study and professor of Harvard Medical School and the University of New South Wales, has discovered by supporting NAD+, that is naturally present throughout our bodies regulates protein-to-protein interactions which control DNA repair, can keep the Cells DNA repair ability at optimal level.
NMN activates Sirtuin 1-7 longevity protein, which improves muscle endurance and strength, protects against heart disease, enhances maintenance of DNA repair, increases mitochondrial function. Sirtuin 1-7 functions are SIRT1 regulates whole-body cholesterol and lipid homeostasis, SIRT2 controls the cell cycle progression at many levels, SIRT3 controls energy demand during stress, SIRT4 regulates insulin sensitivity, SIRT5 regulates protein substrates, SIRT6 promotes the repair of DNA, SIRT7 facilitates the transcription of DNA.
NMN's anti-aging effect recognized by the science community. Researchers from Harvard University, Keio University, Washington University and other institutions have studied and since published numerous articles in "Science", "Nature" and "Cell" academic journals, on NMN being a stable, reliable NAD+ activator and anti-aging molecule.
NMN Plus' antiaging formula includes premium ingredients such as Pterostilbene, a potent antioxidant easily absorbed by human body. It reduces the free radicals that cause aging. PQQ, it has positive effect on the mitochondria. It provides energy, relieves the stress level and pain, it also improves sleep quality. Co10 which is the energy carrier that supports coronary blood circulation, supplies sufficient oxygen to the myocardium, provides sufficient energy for myocardial cells, and restores the blood supply to the heart. L-Carnitine is an amazing amino acid that helps convert fat into energy. NMN promotes anti-aging of blood vessels, increases muscle endurance and strengths, and reduces the risks of heart disease and obesity. It also protects DNA sequence to improve mitochondrial functions. Black Elderberry is packed with antioxidants and vitamins that can boost immune system.
Clinical Studies on NMN's Functionality discovered that it regulates inflammation and cell survival during the immune response and aging. NAD+ is the fuel that helps sirtuins sustain genome integrity and promote DNA repair. It activates B-Klotho. β-klotho is predominantly expressed in the liver. Klotho can help protect against cardiovascular disease and protect against kidney damage. It provides energy NMN increases NAD+ which is an essential coenzyme required for life and cellular functions to operate at optimal level. MN is highly recognized by Science community and the General public. A recent study shown that NMN strengthens our bodies' immune system. When our bodies is attacked by the virus, we are less likely to get sick, and are recovering better and faster.
Competitive advantages of NMN Plus: it is highly bioavailable and stabilized. We use 2020 advanced biocatalysis technology, makes our NMN highly bioavailable and stable. We use science based formula to support mitochondrial energy supply, extend cell growth cycle, antioxidant, eliminate free radicals. It has high purity and enhanced absorption. High Purity NMN in small molecule with enhanced absorption to get in the blood stream faster. 6 Anti-Aging Proprietary Blend act together for maximize anti-aging effect in human body.
What NMN Plus 6000 users are saying, better sleep at night, wake up refreshed; Clean, glowing and smooth skin; Nails are stronger, and grow faster; Hair is thicker, stronger, grow faster, and less grey! Boost energy level without crashing; Hangover relief, faster alcohol metabolism, better morning; Chronic inflammation condition improved; Happier and healthier sex life, improved satisfaction from both parties; Improved conditions for diabetes, high blood pressure, obesity and anxiety.
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